
                                   
                                  Oxygen 
                                    Multistep Therapy involves breathing higher levels of oxygen 
                                    (90%) while exercising on a stationary "spin" bike. 
                                    This treatment is combined with supplements that increase blood 
                                    flow and cellular metabolism and to maximize oxygenation uptake. 
                                    And unlike many similar oxygen therapies, our system is designed 
                                    to give you a high-volume flow of oxygen through a sealed mask. 
                                    This prevents you from breathing ambient air from the room during 
                                    your treatment, and ensures maximum benefit. 
                                   
                                  A 
                                    single session of Oxygen Multistep Therapy lasts about 20-25 
                                    minutes depending on your fitness levels and goals.
                                   
                                  
                                   
                                  Many 
                                    everyday stressors can decrease your blood's "plasma oxygen 
                                    levels" and can cause poor circulation in various parts 
                                    of the body. The oxygen in your blood resides in two places... 
                                    attached to your red blood cells, and dissolved into the fluid 
                                    portion of your blood (the plasma). Dr. von Ardenne's research 
                                    institute did extensive studies on plasma oxygenation, and how 
                                    it reacts to different stressors. Here are some charts below 
                                    showing the effects of specific stressors, and their effects 
                                    on plasma oxygenation.
                                   
                                  Everyday 
                                    Stressors that reduce Plasma O2 (and O2 uptake):
                                   
                                  
                                    
                                      
                                        
                                          
                                             | 
                                           
                                          
                                            
                                              
                                                | The 
                                                  reduction in the arterial resting PO2 by various 
                                                  debilitating effects on the lung-heart system: 
                                                  physical inactivity, excess of stress and 
                                                  physical inactivity, prolonged illness, physical 
                                                  disablement, and flu. [1] | 
                                               
                                              | 
                                           
                                          
                                             | 
                                           
                                          | 
                                      
                                    
                                   
                                   
                                  Dr. 
                                    von Ardenne found that lowered plasma oxygen levels caused capillaries 
                                    (small blood vessels) to narrow. This restriction of blood flow 
                                    contributes to a wide variety of diseases and accelerates aging 
                                    in general.
                                   
                                  Increased 
                                    Oxygen uptake and Blood Circulation after O2 Therapy:
                                   
                                  
                                    
                                      
                                        
                                          
                                             | 
                                           
                                          
                                            
                                              
                                                | O2 
                                                  diffusion parameters at the venous end of 
                                                  the capillaries before (A), during (B) and 
                                                  after (C) O2MT. Rough schematic presentation. 
                                                  Example: 15 min O2MT quick procedure. [2] | 
                                               
                                              | 
                                           
                                          | 
                                      
                                    
                                   
                                   
                                  Whether 
                                    you are fighting cancer, chronic illness, or just want to perform 
                                    at your best, optimizing your plasma oxygen levels and restoring 
                                    proper blood circulation is a fundamental step.
                                   
                                  
                                  
                                   
                                  
                                   
                                  1. 
                                    Athletes:
                                  
                                    People 
                                      who want to increase their athletic performance, will undergo 
                                      O2MT in a different way. Rather than breathing only oxygen rich 
                                      air, we cycle between low oxygen and high oxygen air throughout 
                                      your 15 minutes session on our exercise bike. This "altitude 
                                      contrast" training combines the best of both worlds: the 
                                      physiological stimulation of high altitude training, with the 
                                      metabolic benefits of Oxygen Multistep Therapy. The program 
                                      itself can be conducted in a few different ways depending on 
                                      your goals. So whether you are looking to accelerate your endurance 
                                      gains and VO2 max, or want to reduce the soreness of "season 
                                      fatigue," we can create a plan to suit your needs.
                                   
                                   
                                  2. 
                                    Cancer Patients: 
                                    The relationship of poor oxygenation to cancer growth has been 
                                    studied for decades. Yet, with today's resurgence of metabolic 
                                    research in relation to cancer, the oxygen-cancer connection 
                                    is making its way back into the news [3,4,5]. Modern studies 
                                    are again showing that poor oxygenation in tumor tissues decreases 
                                    patients' chances of survival with conventional therapies [6-11]. 
                                    It can also increase the chances of tumor recurrence [12,13] 
                                    and metastasis [14].
                                  Researchers 
                                    have also shown oxygen therapy to increase the effects of both 
                                    radiation therapy [15], and other natural anti-cancer approaches 
                                    [16,17]. It has also shown to prevent and treat long term damage 
                                    caused by radiation therapy [18]. Oxygen Multistep Therapy is 
                                    also important to maintain your plasma oxygen levels after surgery, 
                                    chemotherapy, and radiation therapy as these therapies can all 
                                    decrease your plasma oxygen levels [19] (see charts below). 
                                    With powerful tools like O2 Multistep Therapy, we can design 
                                    a complementary cancer care protocol to support you every step 
                                    of the way.
                                   
                                  Cancer 
                                    Related Stressors:
                                   
                                  
                                    
                                      
                                        
                                          
                                             | 
                                           
                                          
                                            
                                              
                                                | Examples 
                                                  of the lowering of the arterial resting PO2 by stressful processes of infectious, 
                                                  toxic, and quasitoxic kind. | 
                                               
                                              | 
                                           
                                          | 
                                      
                                    
                                   
                                   
                                  Note 
                                    to cancer patients: While anti-angiogenic 
                                    (blood vessel blocking) therapies (natural or pharmaceutical) 
                                    can be very beneficial, “restoring proper blood flow” 
                                    with O2MT does not mean that it will 
                                    increase blood vessel growth and promote tumor growth. Quite 
                                    the opposite is true. Healthy angiogenesis (blood vessel growth) 
                                    itself is fundamental to life. But angiogenesis in cancer growth 
                                    is deranged [20] and can be thought of as “pathological 
                                    angiogenesis” (disease state induced blood vessel growth). 
                                    Researchers have shown that low oxygen (hypoxia) can stimulate 
                                    this deranged tumor blood vessel growth through proteins called 
                                    “hypoxia-inducible factor” (HIF) [21,22,23]. Rather 
                                    than just blocking this (diseased) blood vessel promoting mechanism, 
                                    Oxygen Multistep Therapy works to remove one of the underlying 
                                    factors (local oxygen deficiency) that stimulates this deranged 
                                    blood vessel growth. In fact, though it was contrary to their 
                                    previous beliefs in blocking tumor blood vessel growth, researchers 
                                    at Oxford University found benefits with a similar approach 
                                    of promoting oxygenation and blood flow to tumors before conventional 
                                    therapies [24]. Researchers at University of Rochester found 
                                    the same effect [25]. Yet, this is something that Dr. von Ardenne 
                                    and other (especially German) researchers had studied for decades. 
                                    Overall, oxygen therapy approached in a specific way, combined 
                                    with a wide range of complementary anti-cancer approaches, can 
                                    be a very powerful complement to conventional cancer treatments.
                                   
                                  What 
                                    is "Accelerated Multistep Therapy"?
                                   
                                  At 
                                    the Center For Acupuncture and Integrative Medicine, we also 
                                    combine Multistep Oxygen Therapy with Whole Body Periodic Acceleration 
                                    (WPA) Therapy, something that we call "Accelerated Multistep 
                                    Therapy." WPA Therapy involves a device called the “Exer-Rest” 
                                    bed, which rocks the patient gently back and forth to increase 
                                    blood flow. You can think of it as a form of “passive 
                                    exercise” that we combine with Multistep Oxygen Therapy. 
                                    This combination was designed especially for those who are undergoing 
                                    conventional therapies for cancers in certain areas of the body.
                                  
                                   
                                  Why 
                                    "Accelerated Multistep Therapy"?
                                   
                                  While 
                                    exercise increases blood flow to the muscles, lungs, and heart, 
                                    it can actually decrease blood flow to internal organs like 
                                    the kidneys, stomach, small intestine, and spleen. Because cancers 
                                    can often be present in these area, we have some patients undergo 
                                    Oxygen Multistep Therapy using Whole Body Periodic Acceleration 
                                    Therapy, instead of exercising on a bike. WPA has shown to increase 
                                    blood flow to the brain (+180%), liver (+86%), stomach, small 
                                    intestine, and kidneys (+53-72%). So depending upon the location 
                                    of your tumor, we can determine which form of Oxygen Multistep 
                                    Therapy will best fit your case.
                                   
                                   
                                  3. 
                                    Computer Professionals/ Knowledge Workers:
                                  
                                    During 
                                      his research in the 1960's, Dr.von Ardenne found something that 
                                      is more relevant now than ever before. 
                                      Though physical inactivity was found to decrease patients' blood 
                                      plasma oxygen levels, physical inactivity combined with stress 
                                      caused even greater drops. Why is this so relevant today? Because 
                                      many of us are "knowledge workers" who spend long 
                                      stressful hours working on the computer. Our brains work extra 
                                      hard, our bodies tend to be motionless for many hours, and our 
                                      breathing tends to be shallow and erratic. This can be highly 
                                      disturbing to our plasma oxygen levels and blood circulation. 
                                      People who exercise intensely right before working on a computer 
                                      can be at even greater risk, because of the "metabolic 
                                      debt" incurred through intense physical exertion.                                  
                                  
                                  If 
                                    you are a "knowledge worker" who suffers from any 
                                    of these symptoms below, O2 Multistep Therapy should definitely 
                                    be considered.
                                   
                                  Poor 
                                  blood circulation
                                  Chronically 
                                    cold limbs or body parts
                                  Frequent 
                                    colds and flus
                                  Muscle 
                                    tightness and spasms
                                  Tension 
                                    Headaches
                                  Any 
                                    condition that is clearly made worse by working long hours 
                                    on the computer
                                  Any 
                                    condition that is clearly made worse by getting a massage 
                                    (including lightheadedness, dizziness, heart palpitations, 
                                    digestive disturbance)
                                   
                                  
                                    4. 
                                      People Fighting Chronic Illnesses (especially stress or age 
                                      induced):
                                  
                                    Oxygen Multistep can benefit a wide variety of chronic illnesses 
                                    because oxygen is at the center of cellular energy creation. 
                                    Here is a list of cases that can benefit from O2 Multistep Therapy 
                                    [26]: 
                                  
                                  Degenerative 
                                    eye disorders
                                  Angina-pectoris 
                                    (heart related chest pain)
                                  Asthma 
                                    and shortness of breath
                                  Liver 
                                    toxicity
                                  Circulation 
                                    disorders
                                  Migraine 
                                    headaches
                                  Wound 
                                    healing
                                  Post 
                                    Illness rehabilitation (heart attack, surgery, infection, 
                                    intoxication)
                                  Reduction 
                                    of side effects of conventional cancer therapies (surgery, 
                                    radiation, chemotherapy)
                                  Rehabilitation 
                                    after illness induced immobility (paralysis, arthritis, 
                                    rheumatism, catastrophic injury
                                   
                                   
                                  5. 
                                    Health Conscious People/ Everyday People:
                                  
                                    Because proper oxygenation is fundamental for cellular energy 
                                    creation, there are only a few that won't benefit from this 
                                    therapy in some way. But in general, here are some of the reasons 
                                    to utilize O2 Multistep Therapy for disease prevention [27]: 
                                   
                                  Reduced 
                                    susceptibility to disease in general
                                  Improved 
                                    skin oxygenation and health
                                  Anti-aging 
                                    effects (decreasing "biological age" by an average 
                                    10 years)
                                  Reducing 
                                    the impact of job stress
                                  Conditioning 
                                    before and or after events involving intense physical or 
                                    psychological stress (surgery, public speaking, competitive 
                                    sporting event)
                                  Normalization 
                                    of oxygen transport capacity in cigarette smokers (especially 
                                    those who smoke more than 4 per day)
                                  Cancer 
                                    and cancer prevention
                                  Immune 
                                    system maintenance
                                  Blood 
                                    circulation stability
                                  Intensification 
                                    of "holiday effect" on overall health
                                  back 
                                    to top                                  
                                  
                                   
                                  There 
                                    are three main differences between these two types of Oxygen 
                                    Therapy:
                                  While 
                                    Hyperbaric Oxygen Therapy and Oxygen Multistep Therapy provide similar benefits, Hyperbaric Oxygen Therapy uses pressure 
                                    to push oxygen into your body. O2 
                                    Multistep Therapy on the other hand, uses physical exertion 
                                    (and supplementation) to pulloxygen 
                                    into your body with it's own natural mechanisms.
                                   
                                  Both 
                                    therapies are very beneficial, but Hyperbaric Oxygen is best 
                                    reserved for those who are severely disabled and/or cannot endure 
                                    physical exertion. 
                                   
                                  High 
                                    quality Hyperbaric Oxygen treatments are more time consuming, 
                                    and much more costly for both the 
                                    patient and provider. 
                                   
                                  O2 
                                    Multistep Therapy is just as effective, more practical, quicker, 
                                    and much more cost effective.
                                   
                                  
                                    
                                      |   | 
                                    
                                    
                                        | 
                                    
                                    
                                      |   | 
                                    
                                  
                                   [1] von Ardenne, 
                                    M. Oxygen Multistep Therapy: Physiological and Technical Foundations. 
                                    Stuttgart, Germany; 1990. pgs. 44-45
                                    [2]von Ardenne, M. Oxygen Multistep Therapy: Physiological and 
                                    Technical Foundations. Stuttgart, Germany; 1990. pgs. 62
                                    [3] http://www.sciencedaily.com/releases/2012/05/120503194219.htm
                                    [4] http://www.nutritionandmetabolism.com/content/7/1/7
                                    [5] http://link.springer.com/article/10.1007%2Fs10863-007-9094-x
                                    [6] http://www.ncbi.nlm.nih.gov/pubmed/8438086
                                    [7] http://www.ncbi.nlm.nih.gov/pubmed/9783886
                                    [8] http://www.ncbi.nlm.nih.gov/pubmed/10717157
                                    [9] http://www.ncbi.nlm.nih.gov/pubmed/11395851
                                    [10] http://www.ncbi.nlm.nih.gov/pubmed/11395850
                                    [11] http://www.ncbi.nlm.nih.gov/pubmed/12067980
                                    [12] http://www.uhn.ca/corporate/ForMedia/PressReleases/Pages/oxygen_in_tumours.aspx
                                    [13] http://www.sciencedaily.com/releases/2009/05/090527151136.htm
                                    [14] http://cancerres.aacrjournals.org/content/56/5/941.full.pdf+html
                                    [15] http://www.utsouthwestern.edu/newsroom/news-releases/year-2013/july/oxytumor-mason.html
                                    [16] http://www.ncbi.nlm.nih.gov/pubmed/23755243
                                    [17] http://www.washington.edu/news/2011/04/04/high-dose-of-oxygen-enhances-natural-cancer-treatment/
                                    [18] http://www.uclahealth.org/body.cfm?id=502&action=detail&ref=675
                                    [19] von Ardenne, M. Oxygen Multistep Therapy: Physiological 
                                    and Technical Foundations. Stuttgart, Germany; 1990. pgs. 44-45
                                    [20] http://gan.sagepub.com/content/2/12/1117.full
                                    [21] http://www.nutritionandmetabolism.com/content/7/1/7
                                    [22] http://www.ncbi.nlm.nih.gov/pubmed/18300418
                                    [23] http://www.ncbi.nlm.nih.gov/pubmed/15245814
                                    [24] http://www.dailymail.co.uk/health/article-1203600/Injecting-oxygen-cancerous-tumours-improves-chances-recovery.html
                                    [25] http://www.urmc.rochester.edu/news/story/index.cfm?id=375
                                    [26] http://med.ardenne.de/?therapien=oxygen-multistep-therapy&lang=en
                                    [27] http://med.ardenne.de/?therapien=oxygen-multistep-therapy&lang=en